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The methods and reporting of the systematic review followed PRISMA13 guidelines.
Reporting of statistical data followed SAMPL14 guidelines.
The last electronic search was on 14 December 2015.Early reversal of vascular occlusion limits the volume of damaged tissue and correlates with outcome.4 By achieving timely reperfusion, thrombolysis improves functional recovery, but only in 33% of patients.5 6 Furthermore, the recanalisation rates associated with intravenous recombinant tissue plasminogen activator (rt-PA)—approximately 46%7—are not ideal, and the use of endovascular interventions may reverse vessel occlusion more effectively and thus help further improve outcomes.Both drug and mechanical endovascular interventions have been evaluated in acute ischaemic stroke.Thrombectomy can be performed using devices that disrupt, aspirate, or retrieve clots.
The procedure can be used alone or as an add-on to intravenous or intra-arterial chemical thrombolysis—that is, adjunctive intra-arterial mechanical thrombectomy.
Electronic identification of reports was conducted in Medline, Embase, Cochrane Central Register of Controlled Trials, Web of Science, Sci ELO, and LILACS.